Heart Model
Cardiovascular Pharmacology Concepts Richard E. Klabunde, PhD

Cardiovascular Physiology Concepts 3e textbook cover Cardiovascular Physiology Concepts, 3rd edition textbook, Published by Wolters Kluwer (2021)

CNormal and Abnormal Blood Pressure, Physiology, Pathophysiology and Treatment book cover Normal and Abnormal Blood Pressure, published by Richard E. Klabunde (2013)

Guided Learning - Antihypertensive Drugs

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  1. How do drugs that dilate blood vessels, reduce blood volume, or reduce cardiac output lead to a decrease in arterial pressure?  click here
  2. How do diuretics decrease blood volume?  click here
  3. What are the differences between thiazide, loop, and potassium-sparing diuretics in terms of their site of action in the kidney and their overall efficacy in lowering blood pressure? click here
  4. By what mechanisms do each of the following mechanistic classes of drugs lower arterial pressure? What specific drugs (generic names) are FDA-approved in each of these classes? Which of the following can cause orthostatic hypotension and reflex tachycardia?

Revised 10/28/2023

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