Heart Model
Cardiovascular Pharmacology Concepts Richard E. Klabunde, PhD

Cardiovascular Physiology Concepts 3e textbook cover Cardiovascular Physiology Concepts, 3rd edition textbook, Published by Wolters Kluwer (2021)

CNormal and Abnormal Blood Pressure, Physiology, Pathophysiology and Treatment book cover Normal and Abnormal Blood Pressure, published by Richard E. Klabunde (2013)

Summary of Drug Classes Used in the Treatment of Arrhythmias

The following table summarizes which antiarrhythmic drugs can be used to treat different arrhythmias. The information was derived primarily from UpToDate on 9/6/22. It is important to note that for a given condition, a particular drug may not be efficacious, and in fact, it may precipitate other arrhythmias or adverse cardiovascular effects (e.g., cardiac depression, hypotension). Therefore, drug efficacy and safety must be carefully evaluated and individualized to the patient when treating arrhythmias.

Sinus or atrial tachycardiaClass II; IV (non-DHP); ivabradineTreat underlying cause if identified 
Atrial fibrillation/flutterClass IA, IC, II, III, IV (non-DHP); digoxinVentricular rate control is an important goal; anticoagulation is required
Supraventricular tachycardiaClass IA, IC, II, III, IV (non-DHP); adenosine; magnesium sulfate 
AV blockatropineAcute reversal only
Ventricular tachycardiaClass IA, IB, II, III, IV (non-DHP) 
Premature ventricular complexesClass ID, II, IV (non-DHP); magnesium sulfatePVCs are often benign and do not require treatment

Revised 11/29/2023

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