Image for Cardiovascular Pharmacology Concepts, Richard E Klabunde PhD

Cardiovascular Pharmacology Concepts

Richard E. Klabunde, PhD

Clinical Disorders:

Therapeutic Classes:

Mechanism Classes:

Also Visit

Cardiovascular Physiology Concepts 3e textbook cover

Click here for information on Cardiovascular Physiology Concepts, 3rd edition, a textbook published by Wolters Kluwer (2021)


Cardiovascular Physiology Concepts textbook cover

Click here for information on Normal and Abnormal Blood Pressure, a textbook published by Richard E. Klabunde (2013)


Tutorial - Antianginal Drugs

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  1. How do antianginal drugs affect myocardial oxygen supply and demand, and how do these actions reduce chest pain?  click here
  2. Which antianginal drugs are used to treat the following types of angina, and what actions of these drugs make them suitable for a particular form of angina?  click here
    • chronic stable angina
    • Printzmetal variant angina
    • unstable angina
  3. What are the mechanisms by which organic nitrate nitrodilator drugs dilate veins and how does this relieve angina?  click here
  4. What is drug tolerance and how does tolerance to organic nitrates affect dosing?  click here
  5. What are common side-effects to organic nitrates?  click here
  6. Which calcium-channels blockers are approved for angina and how do these drugs reduce anginal pain?  click here
  7. What preexisting conditions in patients can be made worse by administering calcium-channel blockers?  click here
  8. Why should calcium-channel blockers not be given with beta-blockers?  click here
  9. Why are beta-blockers useful antianginal drugs?  click here
  10. What are the mechanisms by which beta-blockers reduce heart rate and contractility (inotropy)?  click here
  11. Define the following characteristics for beta-blockers:  click here
    • selective vs. non-selective beta-blockade
    • intrinsic sympathomimetic activity
    • membrane stabilizing activity
  12. What are some common side-effects and contraindications for beta-blockers?  click here
  13. What is the mechanism of the antianginal effect of ranolazine?  click here

Revised 10/24/2022

DISCLAIMER: These materials are for educational purposes only, and are not a source of medical decision-making advice.