Cardiovascular Pharmacology Concepts

Richard E. Klabunde, Ph.D.


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Clinical Disorders:

Angina

Arrhythmias

Edema

Heart Failure

Systemic Hypertension

Pulmonary Hypertension

Hypotension

Myocardial Infarction


Therapeutic Classes:

Antianginal

Antiarrhythmic

Antihypertensive

Cardioinhibitory

Cardiostimulatory

Diuretic
Pressor

Thrombolytic

Vasoconstrictor

Vasodilator


Mechanism Classes:

Click here to see list

 


Click here for information on Cardiovascular Physiology Concepts, a textbook published by Lippincott Williams & Wilkins (2005)


 


Tutorial - Pharmacologic Treatment of Arterial Hypotension

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Pathophysiology of Arterial (Systemic) Hypotension

  1. What are normal values for arterial pressure?  click here

  2. What is the definition of arterial hypotension?  click here

  3. How do changes in cardiac output and systemic vascular resistance influence arterial pressure?  click here

  4. How do changes in blood volume affect arterial pressure?  click here

  5. What can cause arterial hypotension?  click here

Drugs for Treating Arterial Hypotension

  1. What is the rationale for increasing blood volume, stimulating the heart, and constricting the systemic vasculature in the treatment of arterial hypotension?  click here

  2. What are pressor drugs?  click here

  3. What are sympathomimetic drugs and how are they used in the treatment of arterial hypotension?  click here

  4. Why are sympathomimetic drugs contraindicated in patients having coronary artery disease?  click here

  5. What signal transduction pathways are activated for the following sympathomimetic receptor agonists, and how do these drugs increase arterial pressure?
        -  alpha-adrenoceptor agonists
        -  beta-adrenoceptor agonists

  6. How are vasopressin analogs used in the treatment of hypotension associated with hypovolemic, cardiogenic and septic shock?  click here

  7. What is the mechanism of action of vasopressin analogs?  click here

 

 Revised 08/29/06 

 


DISCLAIMER: These materials are for educational purposes only, and are not a source of medical decision-making advice.

© 2005-2008Ed  Richard E. Klabunde, all rights reserved.