Image for Cardiovascular Pharmacology Concepts, Richard E Klabunde PhD

Cardiovascular Pharmacology Concepts

Richard E. Klabunde, PhD

Clinical Disorders:

Therapeutic Classes:

Mechanism Classes:

Also Visit

Cardiovascular Physiology Concepts textbook cover

Click here for information on Cardiovascular Physiology Concepts, 2nd edition, a textbook published by Lippincott Williams & Wilkins (2011)


Cardiovascular Physiology Concepts textbook cover

Click here for information on Normal and Abnormal Blood Pressure, a textbook published by Richard E. Klabunde (2013)


Tutorial - Diuretic Drugs

(NOTE: Turn off or override browser pop-up blockers.)

  1. What is the rationale for using diuretic drugs in the treatment of hypertension, heart failure, and edema?  click here
  2. In heart failure (systolic dysfunction) patients, why does the administration of a diuretic not significantly diminish stroke volume as it lowers ventricular preload and venous pressure?  click here
  3. How do drugs that reduce blood volume cause a reduction in arterial pressure?  click here
  4. How do diuretics decrease blood volume?  click here
  5. What are the differences between thiazide, loop, and potassium-sparing diuretics in terms of their site of action in the kidney and their overall efficacy in lowering blood pressure?  click here
  6. What are the renal mechanisms by which loop and thiazide diuretics produce hypokalemia?  click here
  7. What are the two renal mechanisms for potassium-sparing diuretics?  click here
  8. What are some important adverse side-effects and drug interactions for each of the classes of diuretic drugs?  click here

DISCLAIMER: These materials are for educational purposes only, and are not a source of medical decision-making advice.