Tutorial - Antihypertensive Drugs
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- How do drugs that dilate blood vessels, reduce blood volume, or reduce cardiac output lead to a decrease in arterial pressure? click here
- How do diuretics decrease blood volume? click here
- What are the differences between thiazide, loop, and potassium-sparing diuretics in terms of their site of action in the kidney and their overall efficacy in lowering blood pressure? click here
- By what mechanisms do each of the following mechanistic classes of drugs lower arterial pressure? What specific drugs (generic names) are FDA-approved in each of these classes?
- alpha-adrenoceptor antagonists (alpha-blockers)
- angiotensin converting enzyme inhibitors (ACE inhibitors)
- angiotensin receptor blockers (ARBs)
- centrally acting sympatholytics
- calcium-channel blockers
- direct acting arterial dilators
- ganglionic blockers
- potassium-channel openers
- From the above list of drugs, which ones can cause orthostatic hypotension and reflex tachycardia?