Cardiovascular Pharmacology Concepts

Richard E. Klabunde, Ph.D.


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Clinical Disorders:

Angina

Arrhythmias

Edema

Heart Failure

Systemic Hypertension

Pulmonary Hypertension

Hypotension

Myocardial Infarction


Therapeutic Classes:

Antianginal

Antiarrhythmic

Antihypertensive

Cardioinhibitory

Cardiostimulatory

Diuretic
Pressor

Thrombolytic

Vasoconstrictor

Vasodilator


Mechanism Classes:

Click here to see list

 


Click here for information on Cardiovascular Physiology Concepts, a textbook published by Lippincott Williams & Wilkins (2005)


 


Tutorial - Antianginal Drugs

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  1. How do antianginal drugs affect myocardial oxygen supply and demand, and how do these actions reduce chest pain?  click here

  2. Which antianginal drugs are used to treat the following types of angina, and what actions of these drugs make them suitable for a particular form of angina?  click here
        -  chronic stable angina
        -  Printzmetal's variant angina
        -  unstable angina

  3. What are the mechanisms by which organic nitrate nitrodilator drugs dilate veins and how does this relieve angina?  click here

  4. What is drug tolerance and how does tolerance to organic nitrates affect dosing?  click here

  5. What are common side-effects to organic nitrates?  click here

  6. Which calcium-channels blockers are approved for angina and how do these drugs reduce anginal pain?  click here

  7. What preexisting conditions in patients can be made worse by administering calcium-channel blockers?  click here

  8. Why should calcium-channel blockers not be given with beta-blockers?  click here

  9. Why are beta-blockers useful antianginal drugs?  click here

  10. What are the mechanisms by which beta-blockers reduce heart rate and contractility (inotropy)?  click here

  11. Define the following characteristics for beta-blockers:  click here
        - selective vs. non-selective beta-blockade
        - intrinsic sympathomimetic activity
        - membrane stabilizing activity

  12. What are some common side-effects and contraindications for beta-blockers?  click here

 

 Revised 08/31/06 

 


DISCLAIMER: These materials are for educational purposes only, and are not a source of medical decision-making advice.

© 2005-2008Ed  Richard E. Klabunde, all rights reserved.